Crop loss, eye disease, and skin cancer have been linked to which environmental issue?

The depletion of stratospheric ozone is primarily linked to crop loss, eye disease, and skin cancer. Ozone in the stratosphere plays a crucial role in absorbing the majority of the sun's harmful ultraviolet (UV) radiation. When the ozone layer is diminished, more UV radiation reaches the Earth's surface, resulting in detrimental effects on plant growth, leading to potential crop loss. Additionally, increased exposure to UV radiation is a significant risk factor for various eye diseases, including cataracts, and is a well-documented contributor to skin cancer.

The other options do not have the same direct correlation with these health and agricultural issues. For instance, nitrogen and chlorine monoxide do not primarily interact with UV radiation in a way that causes the same biological effects as ozone depletion does. Similarly, while oxygen is essential for life, its depletion does not directly relate to the increase in UV exposure or the resulting health concerns. Therefore, the depletion of stratospheric ozone is the correct environmental issue linked to the specified health and agricultural concerns.