Which international agreement regulates the production and use of CFCs and related substances?

The Montreal Protocol is the international agreement specifically designed to regulate the production and use of chlorofluorocarbons (CFCs) and other ozone-depleting substances. Established in 1987, this treaty has been pivotal in the global effort to protect the ozone layer by phasing out substances that contribute to its depletion. The protocol sets binding commitments on the reduction of these harmful chemicals, leading to significant recovery of the ozone layer over time.

In contrast, the Kyoto Treaty primarily addresses greenhouse gas emissions and climate change, hence it is not focused on ozone-depleting substances like CFCs. The Council of Nicaea and the Treaty of Ghent are historical agreements unrelated to environmental issues or the regulation of chemical substances. Therefore, the Montreal Protocol is clearly recognized as the most relevant and effective international framework dealing with the challenges posed by CFCs and similar agents.